Prevalence and mechanisms of β-lactam resistance in Haemophilus haemolyticus
نویسندگان
چکیده
منابع مشابه
Divergent mechanisms for passive pneumococcal resistance to β-lactam antibiotics in the presence of Haemophilus influenzae.
BACKGROUND Otitis media, for which antibiotic treatment failure is increasingly common, is a leading pediatric public health problem. METHODS In vitro and in vivo studies using the chinchilla model of otitis media were performed using a β-lactamase-producing strain of nontypeable Haemophilus influenzae (NTHi 86-028NP) and an isogenic mutant deficient in β-lactamase production (NTHi 86-028NP b...
متن کاملNovel mechanisms of resistance to β-lactam antibiotics in Haemophilus parainfluenzae: β-lactamase-negative ampicillin resistance and inhibitor-resistant TEM β-lactamases.
OBJECTIVES To determine the mechanisms of resistance to β-lactam antibiotics in clinical isolates of Haemophilus parainfluenzae. METHODS Twenty clinical isolates of H. parainfluenzae with decreased susceptibility to aminopenicillins were examined and compared with a control group of 20 fully susceptible isolates. In this collection, the presence of amino acid substitutions in the transpeptida...
متن کاملAn invasive Haemophilus haemolyticus isolate.
Haemophilus haemolyticus is generally considered a human commensal and is found in the nasopharynx of a minority of individuals as well as in subgingival plaque (7). Most authors consider H. haemolyticus to be either nonpathogenic (2, 4, 7, 18) or a rare pathogen (1). The latter assessment appears to be based on two reports of endocarditis from the early part of the 20th century (3, 13); howeve...
متن کاملβ-Lactam Resistance and Enterobacteriaceae, United States
Extended-spectrum cephalosporins (ESC) are an important drug class for treating severe Salmonella infections. We screened the human collection from the National Antimicrobial Resistance Monitoring System 2000 for ESC resistance mechanisms. Of non-Typhi Salmonella tested, 3.2% (44/1,378) contained blaCMY genes. Novel findings included blaCMY-positive Escherichia coli O157:H7 and a blaSHV-positiv...
متن کاملHigh prevalence of β-lactam and macrolide resistance genes in human oral Capnocytophaga species.
OBJECTIVES To determine macrolide-lincosamide-streptogramin (MLS) resistance determinants in the Capnocytophaga genus and to describe the prevalence of β-lactam resistance genes in human oral Capnocytophaga species. METHODS Forty-eight Capnocytophaga isolates identified by analysis of 16S rRNA sequences were isolated from subgingival samples from 14 haematology patients (HPs), 11 periodontiti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2013
ISSN: 1460-2091,0305-7453
DOI: 10.1093/jac/dks532